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  • Amphipol A8-35
  • Protein Trapping
  • Properties of MP/APol complexes
  • Functionalized A8-35
  • Others APols
  • Applications
  • Distribution/Training
  • References
  • Overview
  • Folding and Immobilization of Membrane Proteins
  • Applications to NMR studies
  • Biomedical Applications
  • Applications to microscopy

Integral membrane protein/amphipol complexes and high-resolution solution-state NMR spectroscopy.








  1. Membrane proteins associated to amphipols are in their native fold.
  2. Size of the membrane protein/amphipol complexes.
  3. Development of pH-insensitive amphipols.
  4. Organization of amphipols around membrane proteins.
  5. Applications: NMR studies of GPCRs associated to amphipols and their ligands (1/2) .
  6. Applications: NMR studies of GPCRs associated to amphipols and their ligands (2/2).
  7. Acknowledgments.
  8. Summary.
  9. Useful links and contacts.
  10. NMR bibliography (1).
  11. NMR bibliography (2).



This section has been written by Laurent J. Catoire


IBPC-UMR 7099 Laboratoire de Physico-Chimie des Protéines Membranaires 13 rue Pierre et Marie Curie F-75005 Paris, FRANCE
contact: laurent.catoire(at)ibpc.fr