Integral membrane protein/amphipol complexes and high-resolution solution-state NMR spectroscopy.

7_ Acknowledgments.

We express our gratitude to Eric Guittet (Laboratoire de Chimie et Biologie Structurales, Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Gif-sur-Yvette, France) for access to a 700 MHz NMR spectrometer.

We also want to thank Marie-Noëlle Rager (ChimieParisTech, Paris) and Hervé This (UMR 214 INRA, AgroParisTech, Paris) for access, respectively, to Avance Bruker 400 and 300 MHz spectrometers to perform early tests with eicosanoids.

The hydrogenated and deuterated versions of A8-35 used in our NMR studies were synthesized in our laboaratory by Fabrice Giusti