Monday Morning, October 21.
08:45 Welcome & general presentation.
Manuela Zoonens (CNRS, Paris, France)
09:00 Membrane protein structure & stability.
Don M. Engelman (Yale University, CT, USA)
30' + 15' discussion
09:45 Membrane protein stability in aqueous solutions; destabilization by detergents & alternatives.
Manuela Zoonens (CNRS, Paris, France)
30' + 15' discussion
10:30 Coffee break.
11:00 Structures & properties of amphipols. Trapping membrane proteins with amphipols. Properties of membrane protein/amphipols complexes.
Manuela Zoonens (CNRS, Paris, France)
30' + 15' discussion
11:45 Applications of amphipols to membrane protein studies, an overview.
Jean-Luc Popot (CNRS, Paris, France)
30' + 15' discussion
Lunch (12:30-14:00)
Monday Afternoon, October 21.
14:00 The use of amphipols for membrane protein cell-free synthesis.
Francesca Zito (CNRS, Paris, France)
30' + 15' discussion
14:45 Amphipol-Assisted folding of GPCRs and beyond.
Jean-Louis Banères (CNRS, Montpellier, France)
30' + 15' discussion
15:30 Coffee break.
16:15 NMR studies of amphipol-trapped membrane proteins and their ligands.
Laurent J. Catoire (CNRS, Paris, France)
30' + 15' discussion
17:00 Membrane protein crystallization by transfer from amphipols to lipid 3D phases.
Valentin Gordeliy (CNRS, Grenoble, France)
30' + 15' discussion
17:45 Amphipols & mass spectrometry.
Alison E. Ashcroft (U. of Leeds, UK)
30' + 15' discussion