The list below is a non-exhaustive list (do not hesitate to contact us to add your laboratory) of laboratories specializing in bioenergetics in France:
UMR7283, LCB Team Microbial Respiration (Bacterial Chemistry Laboratory, Aix-Marseille University-CNRS). Theme : Integrated study of prokaryotic bioenergetic complexes: from molecule to cell. Investigation of the function, spatial organization, and diversity of bioenergetic complexes. Model species: Escherichia coli, Bacillus subtilis, Lactococcus cremoris, Lactiplantibacillus plantarum. Expertise: Genetic manipulation of E. coli, B. subtilis, and lactic acid bacteria; membrane protein biochemistry; bioinformatics analyses; enzymology; protein biophysics; cell biology; fluorescence microscopy; and more.
UMR7141, P3M (Laboratory of Chloroplast Biology and Light Perception in Microalgae, CNRS/Sorbonne University). Microalgae model species: Chlamydomonas reinhardtii, Phaeodactylum tricornutum, Cyclotella cryptica. Know-how: genetics of microalgae, biochemistry of membrane proteins, biophysics of photosynthesis (fluorometry, absorption difference spectroscopy).
UMR5095, BioDynaMit (IBGC, CNRS Bordeaux). The laboratory is interested in mitochondrial bioenergetic deficiencies secondary to metabolic stress or pathogenic mutations responsible for mitochondrial diseases. Model species: transgenic mouse models, transgenic cell lines (embryonic fibroblasts, human lines). Expertise: characterization of cellular and mitochondrial energy metabolism (high-resolution oxygraphy, measurements of redox potential (NAD(P)H/NAD(P)+) and phosphates (ATP/ADP.Pi), measurement of ROS production, membrane potential, native/denaturing electrophoresis, measurement of mitochondrial dynamics (morphology, distribution and mobility)
UMR5525, TIMC équipe TrEE (Translational microbiology Evolution – Engineering). Research theme Biosynthesis and evolution of isoprenoid quinones and their interactions. Model species : Escherichia coli, Saccharomyces cerevisiae, Pseudomonas aeruginosa, microorganisms. Competences: quantification and characterization of isoprenoid quinones (HPLC-electrochemical detection-mass spectrometry), genetics of E. coli and S. cerevisiae, protein biochemistry, phylogenetic analyses, bioinformatics.
UMR7265, BIAM Equipe Photosynthèse & Environnement, P&E (CEA/CNRS/Aix-Marseille University). Our team studies the molecular factors that regulate the efficiency of photosynthesis and its adaptation to the environment. Model species: plants, micro-algae, cyanobacteria. Expertise: genetic manipulation of micro-algae and cyanobacteria, protein biochemistry, biophysics of photosynthesis (fluorimetry, absorption spectroscopy, gas exchanges).
UMR8226 Equipe Dynamique Membranaire et Modifications Post-Traductionnelles (IBPC, CNRS, Sorbonne University). Research theme: Mitochondrial dynamics (fusion and fission), mitophagy, contact between organelles, Ubiquitin-proteasome system. Model species: Saccharomyces cerevisiae Competences: Fluorescence microscopy, mass spectrometry, genetics of S. cerevisiae, protein biochemistry, cell biology of the mitochondrial network and its association with the endoplasmic reticulum, peroxisomes, etc…
UMR7281, BIP (Laboratory of Bioenergetics and Protein Engineering , Aix-Marseille University, CNRS). Theme: Integrated study of the bioenergetics of microorganisms: from the molecule to consortia, diversity and evolution. Model species: among others, Halorhodospira halophila, Aquifex aeolicus, Shewanella oneidensis and sp. ANA-3, Escherichia coli, Pseudomonas aeruginosa, Solidesulfovibrio fructosivorans, Thalassiosira pseudonana, Chlamydomonas reinhardtii. Expertise: genetics of E. coli, Shewanella, Pseudomonas aeruginosa, Solidesulfovibrio fructosivorans, Chlamydomonas reinhardtii, protein biochemistry, phylogenetic analyses, bioinformatics, protein biophysics, cell biology.
UMR7099, BPM Laboratory (Biochemistry of Membrane Proteins). Theme : Study of the fundamental mechanisms of membrane protein function and membrane dynamics. Model species : Chlamydomonas reinhardtii, Escherichia coli, Pseudomonas aeruginosa, Serratia marcescens. Expertise: microbial genetics and physiology, cutting-edge biochemical and biophysical approaches (cryo-EM, NMR, fluorescence, spectroscopies) and methodological developments (amphipols, optimized bacterial hosts, tools for cryo-EM, reconstitution in mimetic membrane environments)
UMR5248-CNRS-INP, Bordeaux, CBMN (Chemistry and Biology of Membranes and Nanoobjects ). The CBMN has approximately 200 members, divided into 16 groups and four departments. The CBMN’s goal is to understand chemical and biological assemblies and study their properties. Within the “Biomedical Research, Fundamental and Translational” department, the “Architecture of Membrane Complexes” group focuses on the assembly of various efflux pumps from E.coli and Pseudomonas aeruginosa. Expertise includes reconstitution of membrane complexes using detergents and nanodiscs, electron microscopy, and cryo-electron microscopy.
UMR7140 LBS Equipe Chimie de la Matière Complexe (Bioelectrochimistry and Spectroscopy Laboratory, Strasbourg University). Theme: Study of the reaction mechanism of respiratory chain enzymes using coupled electrochemistry/spectroscopy methods. Model species: Escherichia coli, Paracoccus denitrificans, Thermus thermophilus, Mycobacterium smegmatis. Expertise: modification of electrodes and metal surfaces by proteins, direct electrochemistry of membrane proteins, surface-enhanced Raman and Infrared spectroscopies, plasmonics, spectroelectrochemistry