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OFFRES D'EMPLOIS : post-doc, thèse, CDD...
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VOIR AUSSI LES OFFRES D'EMPLOIS
DES UNITES DE L'IBPC :  UMR 7099ET :
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Ouverture d'un poste de professeur à l'Université Paris 7
N° : 0090 |
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04 mars 2008 Position in Berkeley The College of Chemistry at University of California, Berkeley seeks an Applications Specialist for its NMR facility. The facility currently houses five NMR spectrometers (two 500, two 400, and one 300 MHz instruments) and several workstations; a 600 MHz instrument will be installed later this year. Primary responsibility is to provide comprehensive NMR spectroscopy support and user training to approximately 350 users with varying needs and diverse research efforts. Additional duties include assisting with upgrades, writing proposals for new instrumentation, assisting technical staff with spectrometer maintenance, and performing administrative duties. Research opportunities will be available and are actively encouraged. Required qualifications: Ph.D. and 1+ yrs. experience in NMR; strong background in liquids (and, ideally, solids) NMR using Bruker and/or Varian instruments; solid understanding of NMR hardware and software technology, design, and application of complex pulse experiments; experience in structural and conformational analysis. Basic UNIX, C, Perl, Tcl/Tk and CGI background a plus. Excellent written and verbal communication skills are essential. To apply: please send cover letter, resume, and contact information for three references to: NMR Search Committee, c/o Rebecca Egger, Dean?s Office, 420 Latimer Hall, College of Chemistry, University of California, Berkeley 94720-1460. Salary and appointment commensurate with experience. Closing date for receipt of applications is April 11, 2008. The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer.
Rebecca Egger - Assistant to the Dean |
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25 mars 2008 NMR Postdocpositions at Umea University Sweden Further informations are also available online under www.chemistry.umu.se Postdocposition 1: Speciation and dynamics of organic phosphorus in terrestrial and aquatic ecosystems P.I: Dr. Reiner Giesler, EMG. Co-P.I.’s: Prof. Per Persson, Chemistry, Prof. Jürgen Schleucher, Medical Biochemistry & Biophysics, Prof. Mats Jansson, EMG, and Dr. Gerhard Gröbner, Chemistry. Pertinent qualifications Applicants must have a Ph.D. in chemistry or a related field. Key qualifications for this position: - experience in modern spectroscopic techniques, with NMR spectroscopy (liquid-state or solid-state) ranking highest. - experience in handling environmental samples - communication skills in speech and writing, a publication record in a relevant field is a merit – Contact: Reiner.Giesler@emg.umu.se Postdocposition 2: NMR structural studies of transient protein states critical for human amyloid diseases
The project aim is to characterize the structure of
partially folded amyloid precursor states and to reveal the structural
determinants critical for amyloid self-assembly. We propose to study several
medically relevant proteins that form amyloid through different pathways.
This research provides the structural basis for rational development of the
methods aimed at prevention and causative treatment of amyloid diseases. NMR
will be the primary tool in the project complemented by traditional
biophysical and biochemical methods. We are looking for candidates with
documented experience in solution state protein NMR. Experience in protein
expression and purification will be considered as a bonus. We are located in
the Chemistry-Biology Centre of Umeå University. The centre has a 600 MHz
NMR spectrometer equipped with the cold probe, there is an access to a 800
and 900 MHz spectrometers, in addition there is a broad range of modern
biophysical and biochemical equipment. |
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25 mars 2008 Postdoc in Berkeley A
postdoctoral position is available for research in laser-detected NMR/MRI.
Applications range from microfluidics to in vivo human studies.
Contact details can be found on the web page:
http://waugh.cchem.berkeley.edu |
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Post-doc in NMR-based
metabonomic predictive toxicology using bioartificial organs
This is an
exciting opportunity to work as post-doctoral scientist at the Ecole Normale
Supérieure de Lyon. A consortium of academic & commercial partners engaged
in the Centre de RMN à Très Hauts Champs. The project runs for three years.
The position will involve
the following areas of expertise:
This position is available immediately for 2 years. It will be based at the ENS in Lyon. The applicant should be a highly motivated individual aiming to work well in a team, but should also be capable of working in an independent capacity. He/she should be capable of presenting their research to a wider scientific and lay audience. Job descriptions cannot be exhaustive and so the post-holder may be required to undertake other duties which are broadly in line with the above key responsibilities. Contacts
Dr. Marc-Emmanuel Dumas
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17 avril 2008 Ph.D. position for e-NMR in Frankfurt am Main, Germany Job description: You will be part of a European team working toward the deployment and unification of the NMR computational infrastructure in system biology, e-NMR, a project funded under the 7th framework programme of the European Union. Biomolecular NMR plays an important role in life sciences, and structural biology in particular, at both European and international levels. The main objective of this project is to optimize and extend the use of the NMR Research Infrastructures of EU-NMR through the implementation of an e-Infrastructure in order to provide the European biomolecular NMR user community with a platform integrating and streamlining the computational approaches necessary for NMR data analysis. For this, you will work on the development of a uniformed and integrated e-NMR platform that will form the core of the e-NMR infrastructure. The work will be carried in close collaboration with our European partners. Qualifications: You should have a degree in (bio)chemistry, physics, bioinformatics, computational biology or a related field. A background in the computational aspects of biomolecular NMR and structure calculations, experience with Linux and programming skills are an advantage. You should show initiative and the ability to work independently. How to apply: Your application including a CV should be sent by email, post or fax to Prof. Dr. Peter Güntert, Institut für Biophysikalische Chemie, Max-von-Laue-Str. 9 (N220, 105), 60438 Frankfurt am Main, Germany. Fax +49-6979829632 guentert@em.uni-frankfurt.de More Information on the project is available on the website of eNMR:http://www.enmr.eu/
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24 avril 2008 Posted on behalf of Natalie Goto - Victor Terskikh www.nmr900.ca University of Ottawa, Ottawa, Ontario, Canada Post-doctoral
NMR position available in the laboratory of Dr. Natalie Goto, studying
the structure and function of proteins important for regulating bacterial
cell division. Candidates should have a background in biomolecular NMR
spectroscopy and/or protein biochemistry. |
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Postdoctoral Position in Biomolecular NMR Spectroscopy at the Institute of Structural Biology in Grenoble, France. A two year postdoctoral position is available to characterize the structures of viral RNAs and their complexes with human proteins using modern high-field NMR technologies. The project, to be started by the end of 2008, offers exciting opportunities to study how the Hepatitis C virus exploits host cell machineries to replicate and to use the latest, state of the art techniques in cross-correlated and liquid crystal NMR spectroscopy of nucleic acid complexes. The laboratory hosts three NMR spectrometers equipped with cryogenic probes (two 600 MHz and one 800 MHz) and has access to the nearby 900 MHz and the first 1 GHz NMR spectrometers (end 2008) at the European high field NMR centre in Lyon. Applicants will also have access to a fully equipped wet lab for the preparation of isotopically labeled NMR samples. More information can be found on the Institute web site: http://www.ibs.fr/content/ibs_eng/presentation/lab/lrmn/ Grenoble is a pleasant city situated in the heart of the French Alps and houses one of Europe’s most vibrant structural biology communities comprising the European Synchrotron Radiation Facility (ESRF), the Laue Langevin Institute (ILL), the Structural Biology Institute (IBS) and the EMBL Grenoble Out-Station.
Previous
experience in modern heteronuclear NMR spectroscopy and structure
determination of biomacromolecules is required. Experience in studying
RNA by NMR spectroscopy is a plus, but we will consider any motivated
candidate with a good biomolecular NMR background. A competitive salary
(based on previous research experience) is offered with health insurance,
retirement plan and language training allowance. Interested candidates
should forward a curriculum vitae, list of publication and electronic and
postal addresses of potential referees to jerome.boisbouvier@ibs.fr. Application deadline is September 15th.
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05 juillet 2008 PhD Studentship - Department of Earth Sciences - University of Cambridge European Commission Framework 7 Research Studentship (salary + fees paid for EC citizens) The effect of radiation damage on the structure and durability of silicon carbide. The prevention of radioactive contamination of the biosphere by the products of nuclear fission is a major concern for the nuclear industry and governments holding inventories of surplus or waste nuclear materials. An approach may be taken where the retention of fission products and actinides over the long term (repository lifetimes) is engineered into the nuclear fuel design. Silicon carbide coated nuclear fuels are one of these novel fuels. The project involves a detailed assessment of the radiation stability of the fuel coatings, primarily through the application of novel nuclear magnetic resonance methods, but also using X-ray absorption spectroscopy, mechanical analysis and molecular dynamics modelling. The student will be expected to interact extensively with European partners in the Euratom F-Bridge project at the Paul Scherrer Institute (Switzerland), EC JRC Institute for Transuranium Elements, Karlsruhe (Germany), CNRS Orléans (France), CEA Cadarache (France), NRG Petten (Netherlands). The position is suitable for those with first degrees in and earth sciences, materials science, physics, chemistry.
Further information may be obtained form Dr Ian Farnan (ifarnan@esc.cam.ac.uk).
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10 juillet 2008 The BioMagResBank (BMRB), located in the Biochemistry Department, University of Wisconsin-Madison, USA, has an immediate opening a postdoctoral research associate. The minimal requirements are a Ph.D. biomolecular NMR spectroscopy with additional emphasis on bioinformatics. Experience in the calculation and validation of biomolecular structures from NMR data and familiarity with current technologies in computer software development, bioinformatics, and website design are highly desirable. The successful candidate will hold a key position in a multi-disciplinary team, whose goal is to develop and maintain BioMagResBank (BMRB: www.bmrb.wisc.edu), a databank for NMR spectroscopic data on proteins, peptides, nucleic acids, and small biologically relevant molecules. Responsibilities will include developing bioinformatics tools for the organization, query, and distribution of macromolecular NMR experimental data and actively participating as a team member of the Worldwide Protein Data Bank. Work will involve collaborations with scientists in the National Magnetic Resonance Facility at Madison (NMRFAM), the Computer Sciences Departments at the Univ. of Wisconsin-Madison and the Univ. of Athens, Greece, and members of academic and commercial NMR software development groups world-wide. Goals include the construction of a relational database for biomolecular NMR data, the implementation of structure determination and validation software on a computer cluster, and the integration of experimental NMR data with resources available on the WWW. Strong oral and written communication skills are required, because the position entails the writing of grant applications and journal articles as well as presentations at scientific meetings. Extensive background and practical experience in biological NMR spectroscopy and computer software development are essential. BMRB is a resource supported by the National Library of Medicine, National Institutes of Health.
Candidates should send a copy of their curriculum vitae
and request three of their mentors to send letters of recommendation
directly to:
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10 juillet 2008 PhD position available on: Quality control of therapeutic proteins by NMR The use of recombinant proteins in human health care is a growing field, characterized by a rapid progression with 13% of the total drug market. Hormones, vaccines and blood coagulation factors are the first applications of proteins in human health. The growing number of molecules together with the increasing number of companies that are producing therapeutic proteins call for a reinforcement of the quality controls for this kind of drugs. NMR is a powerful tool to investigate the chemical structure of proteins together with their three dimensional fold. This project aims at developing new methods for spectral acquisition and analysis allowing specific spectral signatures to be identified for each therapeutic protein. This project will be developed in collaboration with the NMRTec society. This project has received the support from the pôle de compétitivité "Innovations thérapeutiques". Interested by biophysical and biocomputing methods, the student will use the most recent methods of biomolecular NMR, usually used to study the three-dimensional structures of proteins. After having familiarized himself with these techniques, it will adapt these methods to the acquisition of protein spectra within their commercial formulation. He will interact with software developers in order to define the quality criteria and to automate the spectra acquisition and their interpretation. With this subject, the student will get access to a rather broad range of skills in biophysics and protein chemistry. He will also get familiar with the fast growing field of drug quality control.
For additional information, contact
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The Solid-state NMR group of the Leiden Institute of Chemistry invites applications for a Postdoc position (up to 3 years). Founded by the Research Fund for Coal and Steel of the European Commission, within a research network coordinated by the Fraunhofer-Institut Oberhausen, we aim to study the absorptive properties of coal and link to a molecular structure model. Additional to a MAS NMR analysis of coal samples, optical pumping of noble gasses in order to explore surface properties is intended. The solid-state NMR group in Leiden provides a comprehensive infrastructure including various fields (MAS between 2.3 to 17.6 Tesla), MRI, facilities for illumination in the magnet (Xe lamps, solid-state lasers, OPO) and for low temperature experiments.
Interested candidates should have a strong background
in solid-state NMR, knowledge on optical methods is desirable, interest on
material science and the ability to work independently within the network.
The postdoc would be encouraged to build up his/her own line of research.
The position will be initially offered for one year with the intension to
extend to about three years. The project can start immediately.
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| Postdoc in Biomolecular SSNMR A full-time Postdoctoral Fellow position is immediately available to a highly motivated candidate to conduct research on structural elucidation of membrane proteins (especially G-protein coupled receptors) and pathological protein aggregates. A 600 MHz Varian Inova spectrometer, which is equipped with fast MAS and variable temperature capabilities, is available for this Biomolecular Solid-State NMR research. For more information, please visit http://physics.okstate.edu/zhou/. Qualifications: Ph.D. in Physics, Chemistry or related fields. The candidate is expected to have strong solid or solution NMR background. Experiences with protein expression and purification are a big plus. To apply: Please send a cover letter, CV and the names and contact information of three references to Dr. Donghua Zhou by email: donghua@okstate.edu.
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| Postdoctoral position in biological solid state NMR A postdoctoral research position in biological solid state NMR is available at the Department of Structural Biology at the University of Pittsburgh School of Medicine. The group of Patrick van der Wel uses solid state NMR to study various biological topics, predominantly through the use of magic angle spinning (MAS) solid state NMR. Particular research interests inlcude (1) Structural membrane protein studies focused on the interplay between the lipids of the lipid bilayer and the membrane-bound protein, (2) Investigations of amyloid fibril structure and formation. The group has specific access to Bruker 800 and 600MHz magnets, which are well-equipped for solid state NMR, with multiple MAS as well as static solid state NMR probes. The department also features collaborative research groups with expertise in a variety of structural techniques, including solution state NMR, (cryo) EM, and X-ray crystallography. It is housed in a new research building and includes state-of-the-art equipment and wet lab resources. For more information see: *http://www.pitt.edu/~pvdwel/positions.html*Or contact Patrick van der Wel at: pvdwel@pitt.edu
Patrick C.A. van der Wel, Ph.D.
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TENURE-TRACK POSITION IN THE LABORATORY OF CHEMICAL
PHYSICS AT THE NATIONAL INSTITUTES OF HEALTH (NIH), BETHESDA, MARYLAND The Laboratory is located on the main intramural campus of the NIH in Bethesda, Maryland, just outside Washington, D.C. The Principal Investigators in the Laboratory are: Artur Adib, Philip A. Anfinrud, Adriaan Bax, G. Marius Clore, William A. Eaton, Gerhard Hummer, James Hofrichter, Ira W. Levin, Attila Szabo, and Robert Tycko (Scientists Emeritus: Edwin D. Becker and Robert W. Zwanzig).
Interested applicants should send a Curriculum Vitae and
list of publications, copies of selected publications, a summary of research
accomplishments, a plan for future research, and three letters of reference
by email to <eaton@helix.nih.gov> or by mail to:
Dr. William A. Eaton, Chief, Laboratory of Chemical Physics, Building 5,
Room 116, National Institutes of Health, Bethesda, MD 20892-0520. HHS and NIH are Equal Opportunity Employers.
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novembre 2008 Postdoctoral position in bacterial pathogenesis - Vrije Universiteit Brussels A post-doctoral position in membrane protein structural biology is available at the laboratory of Structural & Molecular Microbiology, Structural Biology Brussels (VUB / VIB), Brussels – Belgium Our group studies the structural molecular biology of bacterial adhesins and cell surface filaments with respect to their biosynthetic pathway and function in bacterial pathogenesis, with the ultimate aim of developing new generation virulence-targeted antimicrobials (see Remaut et al. 2006, Mol. Cell22, 831-842; Pinkner et al. 2006,Proc Natl Acad Sci USA.103, 17897-902; Fronzeset al. 2008,EMBO J.27, 2271-80 and Remautet al. 2008,Cell133, 640-52 for relevant references). Further information on: http://www.structuralbiology.be/research/adhesins We are looking for a highly motivated structural biologist (X-ray/NMR) or candidates with experience in membrane protein expression and purification with a strong interest in structural biology. The successful candidate will take part in the structural study of host-pathogen interactions in the human pathogen Heliocobacter pylori, the leading cause of peptic ulcer disease and a major risk factor for the development of gastric cancers. VIB (the Flanders Institute for Biotechnology) is an interdisciplinary non-profit research institute based at 4 Flemish universities (Ghent University, K.U.Leuven, the University of Antwerp and the Vrije Universiteit Brussels) and employs a vibrant community of over 1000 life scientists. Informal enquiries and applications (including CV, letter of motivation as well as the contact details of at least 2 references) should be directed to Dr. Han Remaut: hremaut@vub.ac.be
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21 novembre 2008 A postdoctoral (two years) position is available in the Nuclear Magnetic Resonance Laboratory (LRMN) at NeuroSpin, CEA, Saclay, France (http://www-dsv.cea.fr/neurospin/) under the supervision of Luisa Ciobanu and Denis Le Bihan. NeuroSpin currently houses 3T and 7T Siemens clinical scanners and a 7T Bruker PharmaScan. At the end of 2009 it will house the world’s first 17T horizontal bore animal scanner. The position will focus on the development of novel, primarily diffusion-based techniques for magnetic resonance microscopy and the investigation of cellular and tissular diffusion contrast at ultra-high magnetic field. Pulse sequences will be initially developed for the 7T scanner and then transferred to the 17T system. Applicants must have a doctorate degree in engineering (biomedical or electrical preferred), physics, computer science, or other relevant discipline. Previous experience in MRI and pulse sequence design is desirable.
Interested individuals should e-mail their CV and the contact information of
at least two recommenders to Luisa Ciobanu (luisa.ciobanu@cea.fr)- |
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10 décembre 2008 Un poste de professeur sera ouvert au concours pour un poste a l'université de Rennes1. Le candidat retenu intégrera l’équipe RMN et Interactions Lipides Protéines de l’UMR CNRS 6026. Le domaine de recherche est centré sur les modifications structurales de peptides ou de protéines en interaction avec des modèles membranaires modèles (micelles et liposomes de différentes compositions lipidiques). L’objectif de ce poste est de développer l’utilisation de la modélisation moléculaire pour la détermination des structures en environnement lipidique. Le candidat retenu aura des compétences attestées en modélisation moléculaire et une bonne maîtrise dans l’articulation des données RMN et la résolution des structures. Des projets collaboratifs seront aussi développés au travers de la plate forme PRISM, dont l’équipe assure le suivi, qui a pour mission de résoudre les structures de peptides ou de protéines. Des collaborations avec les équipes de chimie pharmaceutique sont déjà établies et le candidat sera aussi invité à renforcer ces liens, puisque la modélisation moléculaire constitue pour eux aussi un axe à favoriser. Contact: Arnaud BONDON, Equipe RMN-ILP, UMR CNRS 6026, tél.: (0)2 23 23 65 61, arnaud.bondon@univ-rennes1.fr
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17 décembre 2008 Poste de Professeur Université Pierre & Marie Curie – Recrutement en 2009 UMR 7009 Biologie du Développement UPMC – CNRS – Villefranche/mer Nature de l’emploi : Professeur Section(s) du C.N.U. :65 Profil : Biologie cellulaire et moléculaire et physiologie du développement des organismes marins L'UMR 7009, située au sein de l'Observatoire Océanologique de Villefranche, possède une expérience unique en France et une expertise reconnue au plan international sur le développement d'organismes marins. Le laboratoire travaille sur des modèles d'étude classiques en biologie de la reproduction et du développement, en biologie cellulaire et moléculaire (Oursins, Ascidies), ou qui sont susceptibles de le devenir (Cnidaires, Appendiculaires). Les enseignements du Master devant s'appuyer sur la compétence et la qualité des équipes de recherche, la présence d'enseignants de l'UPMC dans notre Unité permettra un meilleur contact entre les filières de formation et nos groupes de recherche et donc une transmission plus importante et plus efficace de notre savoir faire à des étudiants de divers cursus. Ce contact avec l'enseignement est d'une importance capitale pour une UMR. Enseignement : Le nouveau titulaire résidera à Villefranche, mais dans le cadre des cursus UPMC et pour les besoins du service, il sera susceptible d'effectuer une partie de son enseignement sur le campus Jussieu. Il devra contribuer à l'enseignement de la biologie du développement, et biologie de la reproduction en particulier en ce qui concerne les organismes marins, ainsi qu'aux enseignements de biologie cellulaire et de biologie moléculaire. Il pourra s'intégrer dans des enseignements des mentions 6 et 7 du master. Sur le campus de Villefranche, le titulaire devra : 1. prendre en charge l'organisation et une large part de l'enseignement du stage du Master UPMC (Mention Biologie Moléculaire et Cellulaire, Spécialité Biologie Cellulaire et Développement, Parcours Biologie du Développement) , (UE d'Ouverture + UE d'Analyse scientifique = 12 ECTS, 10 jours à plein temps) 2. après discussion avec l’Université et les autres Observatoires Marins, mettre en place et assurer des enseignements spécialisés comptants pour des ECTS, ouverts à l'UPMC et à d'autres Universités, et des stages, ateliers ou cours intensifs propres à notre discipline. (Cours, ateliers récurrents internationaux. Développment d'un PhD program international au sein des station marines de l'UPMC). Sur le campus Jussieu, le titulaire devra : 1. contribuer à l'enseignement en biologie cellulaire et moléculaire, en biologie du développement et en physiologie. 2. contribuer au travail du Comité de parcours Biologie du Développement M2. 3. prendre en charge l'organisation et une large part de l'enseignement d'une UE que nous avions proposé ("Apport des modèles marins en Biologie cellulaire et moléculaire" 3 ECTS, une semaine), destinée à présenter les apports des modèles marins à travers leur utilisation dans les 3 stations marines de l'UPMC. Cet outil serait extrêmement utile aussi bien pour les étudiants que pour les laboratoires et son contour devrait être défini précisément en concertation avec les enseignants des Stations de Roscoff et Banyuls. Recherche et direction de l’UMR : Le mandat du directeur actuel de l’UMR se terminera fin 2008. Le candidat retenu pourrait être amené à assurer la direction de l’UMR dans le futur. Les grandes thématiques de l'UMR actuelle sont : cycle cellulaire méiotique, maturation ovocytaire, déterminants du développement, mise en place des axes embryonnaires, régionalisation de l'embryon précoce, rôle des voies de signalisation dans la spécification et la différenciation des lignées cellulaires, fonction de gènes régulateurs au sein de réseaux d'interactions, morphogenèse. Le candidat devra conduire un programme de recherche en biologie moléculaire et cellulaire d'organismes marins déjà étudiés au laboratoire, ou sur de nouveaux modèles susceptibles d'y être développés. Une bonne expérience dans ce domaine sera un avantage. Le candidat devra avoir une très bonne connaissance des problèmes de développement en général. L'étude de mécanismes de développement pourra être réalisée dans le contexte de l'évolution (Evo-Devo). Unité de recherche d’accueil : UMR 7009. Nombre d’enseignants chercheurs : 1. Nombre de chercheurs : 13 Contacts : Christian Gache (Directeur de l'Unité) christian.gache@obs-vlfr.fr ; 04 93 76 37 96 |
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